Exposed: cells’ sugary secrets

Dark secrets of tobacco company exposed.

Secrets of tubule engineering by epithelial cells.

M any vital epithelial organs develop in the embryo from simple tubes that branch and ramify into complex, treelike structures. This tubular morphology greatly increases the total cellular area available to the body for metabolic processes, such as nutrient and gas exchange, while reducing the distances over which substances have to travel (1). Epithelial organs such as kidney and mammary gland...

Secrets of drug resistance in NSCLC exposed by new molecular definition of EMT.

Non-small cell lung carcinoma (NSCLC) metastasis and drug resistance has been associated with epithelial-to-mesenchymal transition (EMT). This study reports the development of a robust gene expression signature of EMT in NSCLC and reveals new insights into the key molecular events that underlie EMT and drug resistance in NSCLC.

Deep secrets

be hypothesised that adaptation to pollinators has been a driving force behind the diversification of some of the major elements of the southern African flora, " Johnson writes. Southern African flowers are known to be attractive to a range of species from long-probscid flies, oil-bees, hawkmoths, butterflies, birds and rodents. Many of these pollination interactions have been characterised in ...

Cigarette secrets.

-Evidence is presented that microscopic tumours (of a transplantable murine mammary carcinoma, M8013X) grow faster than larger, palpable, tumours. Microscopic tumours are also more radiosensitive than larger tumours. The decrease in radiosensitivity in larger tumours is prevented to a large extent by misonidazole, which has no significant effect on the radiosensitivity of microscopic tumours. T...